He predicted that if every American 50 and above with Covid received a course of either Paxlovid or a treatment known as monoclonal antibodies, daily deaths might fall to about 50 per day, from about 400 per day in recent months.ĭr. Ashish Jha, the White House Covid response coordinator, told me. “A large chunk of deaths are preventable right now with Paxlovid alone,” Dr. Today’s newsletter will dig into both issues. The second explanation is that many Americans, especially Republicans, still do not take Covid seriously. The first is that the public discussion of them has tended to focus on caveats and concerns, rather than on the overwhelming evidence that they reduce the risk of hospitalization and death. There seem to be two main explanations for the drugs’ underuse. Until then, other Times journalists will be writing The Morning, and I look forward to reading their work along with all of you.Ī worrisome pattern has emerged with Paxlovid and other drugs that reduce the severity of Covid: Many people who would benefit most are not receiving the treatments, likely causing hundreds of unnecessary deaths every day in the U.S. A Cerebral rival, called Done, is also facing Drug Enforcement Administration scrutiny, The Wall Street Journal reported.Ĭhris Savarese, a spokesman for Cerebral, said the company had ceased prescribing controlled substances to new patients and had not been accused by any government agency of wrongdoing.First, a programming note: This is my last newsletter before starting a book leave. Truebe was not fired as an act of retaliation, but because he was a “poor performer.” The company has received a subpoena from federal investigators reviewing its compliance with the Controlled Substances Act. Truebe also claimed the company had duplicate patients in its database, suggesting that some were seeking prescriptions to resell.Ĭerebral, valued at over $1.2 billion this summer, said in a court filing that Mr. patients, something he considered “not safe or legal,” according to court records. A former vice president of Cerebral, Matthew Truebe, filed a wrongful termination suit against his former employer, claiming that a company goal was to prescribe stimulants to 100 percent of the company’s A.D.H.D. One such company is Cerebral, which is based in San Francisco. There is little data on start-up telehealth companies that have drawn criticism for rapidly prescribing a variety of medications, including Adderall. Even then, some come up short and, without their medications, may miss deadlines or forget important tasks if they are working in a high-pressure situation. He said his office has had to reissue them in different dosages to help patients receive treatment. Goodman said patients report almost every day that they are unable to get prescriptions filled. “With a controlled substance, it’s harder for patients to call around and find a pharmacy that has product for them,” Ms. Any given pharmacy might risk raising red flags with the Drug Enforcement Administration by doubling its supply, said Erin Fox, an expert on drug shortages at the University of Utah. While a number of companies make Adderall and generic versions, pharmacies may find it difficult to pivot to other suppliers because of amphetamine’s status as a controlled substance that typically includes restrictions on its use and monitoring of prescription orders. He received $18,000 in 2021 as a consultant for drug companies. Goodman, who is also an assistant professor of psychiatry at Johns Hopkins University School of Medicine. “I can understand why there are shortages, because there’s an increased demand of people who are seeking these medications,” said Dr. In addition, he said, the telehealth start-ups made it cheaper and less time-consuming to get a diagnosis, although he questioned whether all of those were accurate. He said growing awareness about the condition appears to be leading to a surge in demand for medications. David Goodman, director of the Adult Attention Deficit Disorder Center of Maryland, said about 4 percent of adults and 8 percent of children have attention deficit hyperactivity disorder, and large numbers of them go untreated - roughly 70 percent of adults and 40 percent of children. The teenage mental health crisis that exploded during the pandemic put a spotlight on sharp increases in some prescriptions, like Adderall.ĭr. Over the years, concerns have been raised about the overprescribing of Adderall for children and young adults with A.D.H.D., and about its abuse as a study aid among college students. Total prescriptions rose by about 16 percent, to 41.2 million last year from 35.5 million in 2019. The number of Adderall and generic-equivalent prescriptions has been rising in recent years, according to figures from IQVIA, a data analytics company.
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